Research position in Normal and Pathological/Cancerous Stem Cell Biology and Radiobiology, at the French Alternative Energies and Atomic Energy Institution (CEA)

The position will be attached to the Stem Cells and Radiation Service (SCSR), which is one of the three services of the Department of Cellular and Molecular Radiobiology (DRCM, https://jacob.cea.fr/drf/ifrancoisjacob/Pages/Departements/IRCM/IRCM.aspx), which is part of the Francois Jacob Institute of Biology and the Fundamental Research Directorate of the CEA.

Located in Fontenay-aux-Roses (10 km from Paris city centre), the DRCM (Department of Clinical Research and Management) dedicates its work to research in radiation biology, DNA repair, genomic stability, tissue regeneration, and oncogenesis, using cellular and preclinical models. The SCSR (Center for Scientific and Clinical Research) brings together laboratories working on the biology of several types of somatic (brain, blood, skin) and germline stem cells in humans and mice. The SCSR is interested in their tissue regeneration potential, their responses to ionizing radiation, and their permissiveness to cancerous transformation. The SCSR focuses these themes on cellular and molecular mechanistic aspects with the aim of translational applications within regional, national, and international clinical- scientific networks.

The recruited Researcher, a future Principal Investigator (PI) in Stem Cell Biology and Radiobiology, will work in the field of germ cells or hematopoietic cells and contribute to research with a strong fundamental and translational impact. They will develop cutting-edge projects primarily within the SCSR laboratories working on hematopoiesis (Team Niche, Cancer and Radiation in Hematopoiesis, PI: F Pflumio) or on germline differentiation (Team Germline Differentiation, PI: G Livera).

The responsibilities of this position are to:

• Develop, implement, and supervise an innovative project within the aforementioned themes, related to the biology of hematopoietic (stem) cells or germ cells, their differentiation, cancerous transformation, and sensitivity to ionizing radiation in line and at least as a start integrated within the projects of the host team.
• Manage students and postdoctoral researchers.
• Ensure the autonomy and sustainability of the project by securing independent funding at the national and international levels.
• Write articles and scientific journals and participate in national and international conferences.
• Participate in the weekly meetings of the host laboratory and in the activities of the Service/Department.
• Establish and develop collaborations with public and/or private partners.

The candidate, holding a PhD in Science, must demonstrate postdoctoral experience with expertise in germinal or hematopoietic cell biology, normal and pathological/cancerous cells, and skills in radiobiology and/or DNA repair. The candidate must be experienced in handling animal (rodent) and/or human cell models. Knowledge of bioinformatics, particularly high-throughput ‘omic’ data analysis, will be a significant asset. As a future Principal Investigator, the ability to independently manage research projects and supervisory experience will be considered. Recognition in the field of expertise, demonstrated through presentations at conferences and/or participation in national/international scientific networks, will be important for this position.

The attractive perks of a research position at DRCM/CEA include:

• A stimulating work environment within a versatile research department.
• Technological support through multiple expert platforms.
• Training opportunities to enhance skills and boost career advancement.
• A location near Paris, easily accessible by public transport (tram, metro, bus, RER).
• Practical benefits: company restaurant, 75% reimbursement of public transport costs, dedicated shuttles from Paris, and much more

Applications (cover letter, CV, list of publications, summary of scientific achievements, project propositions to develop in the future lab (2 pages), contact information for 3 references)
should be sent @: secretariat-u1274@cea.fr

• Application deadline: April 30, 2026
• Shortlisted candidates interviewed in June 2026.
• Position available: September 2026